I personally use a 410 with an 8 space rack stacked on top. The only time i lift either is in and out of the car, the rest of the time i roll it around on casters. The wheels on the 410 are small and don't roll really well on asphalt but my driveway is concrete and most of the venues i play have a concrete sidewalk i can roll it on just fine. I've used just about everything from multiple 210 cabs up to an 810. The 410/212 size cab with 4 wheels works best for me. With tilt and roll style cabs like my old ampeg 810e, ampeg 410hlf, and swr610 it varies. Out of the tilt and roll cabs the 810 was actually the easiest to roll, the 410hlf was miserable to roll because it was much shorter. The problem with all those cabs is i had to bring in my rack separately. With 210/112 small cabs my problem was they are to small to roll around by themselves so you need something else to help move them, as shown above. Small cabs are nice if you live on the 3rd floor of an apartment building and have to go up and down stairs, 810s are nice with a band trailor with a fold down door/ramp. But for transporting in a car I'm happy with my rig.
When i get to the venue i set my cab on the ground, stack my rack on it, then put my bass i bring in a gig bag on my back. If i use effects i bring them in a backpack. Its a one trip load in, no deadlifting gear into the venue, no multiple trips to outside.