I've only owned one combo amp and it was a Fender Bassman 25. From that I quickly went to full blown amps. For me they were a much better fit. I could essentially have a rig of comparable size to a combo amp but I could also be more scalable. I could get bigger as needed. Then when gear began to get smaller & lighter while still maintaining the power I needed, I stopped looking at combo amps all together. I'm sure that someone still values combos but give me separates.
DSFDF - as they say.
I went full circle - Combo to Preamp + Power Amp + Cab to Head + Cab to Combo.
I think the Quilter makes it very tempting to go back to Head + Cab(s) again, I'm still weighing options.
I got rid of most of my bass equipment, because I thought I was done with playing bass; I bought a classical guitar.
But the bass bug was stronger than my will, so I bought a new bass guitar and a Two Notes Opus (highly recommended - great sounding unit).
I've been trying to save money and decide where to go from here whether Head + Cab(s) or Combo or Active Cab (like GRBass).
The older I get, the more important keeping load in, setup, teardown, load out as simple as possible.
Ideally, I could just plug in what I've got to a good PA, but you cannot count on that situation long term.
Medical bills and vehicle maintenance have put a crimp in my savings, anyway, I'm still considering.
For the Head + Cab option, I'd love a BBV803 + either - a Barefaced Super Compact or a GRBass AT 210V+ Cab (I like what I've heard of the GK Neo IV 115 as well - though just a tad more voiced than the other two cabs mentioned).