when you say lows, do you mean 'fundamentals' or the beef of the low mids?
I would suggest, that if you're looking for tha big open, float you around the room kind of low, that you cut the low mids/upper bass and boost the ultra lows...but that's just me. If you can make sure your sonic spectrum lets you use your headroom evenly then you should have no problems getting deep lows.
I've got some super lows with a 110 that have outdone the 1x18, 2x10 cab i used to have. It all depends on what you have and how you can use it.
Anything sounds great coming out of a GK. I love my yamaha and I play low end basses. As long as you have enough headroom, you should be able to make anything work.
And if you have a really good cheater pedal (sansamp/preamp) then you could even get away with just using a power amp.
I'd say that as long as you're playing with more than 200W you should be good, as far as playing in a jamspace with a drummer.