If you don't know what a bad tube sounds like, why do you assume it's a bad tube?
Anyway, to me that sounds way more broken than a bad preamp tube, BUT 12AX7s are cheap and ubiquitous, so it couldn't hurt to try.
But I would do these 2 things first because they are free and a lot easier than opening the thing up.
Assuming you have another (working) amp and both have effects loops, run the preamp of the other amp into the power amp (fx return) of the SWR. if that solves you're problem, now you've narrowed it down to the preamp section of the SWR (could then be the tube or something else).
If that doesn't solve your problem, the next step is to do basically the same test, but instead of a different preamp, use a different speaker. This requires the combo to have both a defeatable interal speaker, as well as an external speaker jack (unless you rig it up). If the SWR electronics sound great through another speaker cab, but not its own, you have your realm of malfunctioned narrowed down there.
If THAT doesn't solve your problem, you can do the same as test #1, but flipped around, so SWR pre into another power amp. If possible to use the SWR internal speaker that would be ideal.
What I'm getting at is you isolate each major component of the SWR by taking it out of the system and see if the problem goes away until you figure out where the problem is coming from. If those 3 tests don't bring forth an answer, you may need to do another round using just one system of the SWR at a time (pre, power, and speaker).