Ron Wickersham and Alembic were working under an imprimatur from Owsley Stanley to improve the Dead's sound, both live and recorded, as Alembic covered all those aspects: The instruments, the PA (the famous 'Wall of Sound') and Alembic recorded several of the early records. Ron was a military trained former Ampex design engineer, and for 'Europe 72' they carried a 24 track recording board and Ampex 2" recorders around the tour.
He found that the Dead's guitar and bass pickups lacked a lot of frequency response, and found that with far fewer turns, frequency response improved dramatically but . . . . not enough wire/coil/output to drive conventional amp front ends. This is where the onboard electronics came in to bring the output up to normal levels, with preamps added internally to do this. This was indeed the genesis of low impedance pickups with a preamp, 'active' electronics, just one more thing that Ron and Alembic pioneered.
So on Alembic instruments with the Series pickup sets, the DS5 power boxes do two things: With AC power, the headroom is far greater than any other method, and the frequency response and headroom is several orders of magnitude past conventional pickup arrangements, but then the rub is it requires the 5-pin cable, which can complicate things. This is why these axes have a brutally clean tone, they're virtually impossible to distort without pedals. Great for bass, not so hot for guitars if that's what you're after.
These instruments include an 'emergency' double 9v battery arrangement to get you through a gig should the power box or cable fail, but these use comparatively a lot of power and you'll be lucky to get much more than 5 or 6 hours out of new batteries.
Their later instruments (they lack that smaller 'middle' pick up, actually a hum canceller for the single coil Series pickups) are a bit more conventional, don't require the 5-pin cable, use a regular mono guitar cable and a single 9v battery, and battery life is comparable to any other bass out there. I'd change mine at New Years and 4th of July and never had a problem, ever, on my Spoiler Five and Elan Five.
Alembics are a completely different world in some ways. I always say they're not for everyone, but if you 'get it', there is nothing, but nothing like an Alembic.