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Zoom B2 Effects Loop or Not

Just bought my first multi-effects thing, a used Zoom B2. I'm fairly new to bass and totally new to pedals so the Zoom will be used only at home. I'm more interested in amp / cab sims than effects at this point. Effects and patches will happen later. My question is do I run the B2 through the Effects Loop of my Fender Rumble or straight into the amp? I read some threads for an answer but get lost real fast in the responses and end up knowing nothing more than when I started reading the stuff.