I agree with Chuck3, amplification is the least cut and dry subject I can think of that gets battered about on this forum.
Some rigs that have served me very well in the past
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AI Contra Series I. I ran out and bought one of these as soon as I heard and played through one. This amp was a game changer. My Juzek, Innovation Piccato Orchestras, old original Realist, George L fat series cable, a power cord, and a couple volumes of pocket changes went with me to about 1500 jobs (read; years and years) before I got tired of the setup and started changing stuff. It was like an old Honda, nothing wrong with it, I just got tired of a good thing!!
AI Clarus Series III, with old Ramsa 8" PA cab, EA Wizzy 10, or as a front end for a QSC KW122. The Clarus has been my main tool for amplification for the last 4 or 5 years. The above mentioned cabs, a K&K bassmax, a mess of other pickups, and now the Troll Mic. I almost bought another that came up second hand, but then I realized that it would preclude getting a new AI when this one finally gives up (Do they? My last one worked fine when I sold it!).
Looking ahead, I recently got a Flex Pre, and I must say, in testing, that with a K10 was pretty hard to beat. I have yet to use this rig on a gig, but the Flex with the KW122 was stellar. I'm also very curious about the Flex cab, I haven't had a chance to use one yet.
I guess I'm an AI guy, eh?