I'm still digging my old school style hybrid heads and medium to lower tuned 4x10 cabs. I feel like my Trace head over a couple Genz XB cabs would be lethal. Or my GBE 750 through 4 Goliath IIs. Is that practical? Not so much. Is it awesome? Yes. I don't have anything against lighter class D stuff, but most of those available just dont grab me (MB500... yawn. PF500... yawn. Rumble 500... yawn.). There are some less common ones that I'm intrigued by, like the Laney Nexus (but I'd rather have the big Nexus all tube amp).
Music is art, so to me, practicality is really the last thing to consider, because art is not "practical" at all. If it sounds good, and hopefully looks cool, as long as it's not too insanely impractical, I'm down. If I needed a team of roadies to play a $50 gig, that doesn't work. But if I need a bandmate to help me carry a cab in or out, that seems to be within the bounds of what's reasonable. My 43 pound head would certainly be cooler if it was 15 pounds lighter, but I'm not aware of too many amps out there with the array of features it has and that have as interesting a sound as it does. And I also tend to like gear that isn't trendy and super common (ie fender, etc...), so stuff like the Trace line from about 8 or 10 years ago that nobody seems to have even though it's awesome is right in line with what I like. My main basses are a carvin and a yamaha (plus another yamaha that's 35 years old, plus another carvin that's about 30 years old, and then a kramer aluminum neck). I never owned anything "fender" until a couple weeks ago when I traded a pedal for one, because why not. So trying to fit into the "zomg I needz to carry my whole rig in one hand in half a trip" crowd completely falls flat for me because WHAT DOES IT HAVE TO DO WITH THE MUSIC? If it's not making the music better, I'm not interested. And my killer "old" amps and cabs that I get for half what they should go for because they're no longer "cool" but are in fact actually amazing, make my music better and I'm happy to have them, and I really only think about how heavy they are for about 2 or 3 minutes on any given practice or gig day. The rest of the time I'm just smiling at how great the stuff sounds.