The Anagram is extremely easy to use. You could figure out most of the functionality immediately without a manual. It's really that easy. It's a touchscreen with knobs. You tap blocks to edit them, you drag them to move them in the preset, you tap a blank spot to add a block, and the knobs control the things under them.
The hardest thing to understand if you've never used a modeler before is scene mode, which is essentially a preset within a preset, where you can toggle multiple blocks on/off and/or adjust the settings all with one stomp switch. Most modelers have something like that so it's not unique to the anagram in any way, but it's a big change if you're coming from analog pedals. It's also completely optional. You could just use stomp mode if you want each switch to toggle a single effect