I don't necessarily recommend it, but I have done it. I learned to play through a blackface Fender Twin Reverb. The original speakers were blown and I played through a Traynor YC-810 (Big-B). I eventually bought a pair of JBL E-120s to load into the Twin. I believe the E120s were rated at 150W RMS each, so that's 300W RMS of power handling. Of course they could not handle anywhere near that much bass. The Twin is considered an 85W amp. The E120s seemed to handle almost the full clean power of the amp as long as I kept the bass control at 4 our lower.
As far as I know, open back cabs actually behave like a ported design. However, I believe resonance is unusually high for a bass cab, so an open back cab can't give you any serious lows.
I used the Twin a variety of ways. My bass was a Rick 4001, and I ran Ric-O-Sound with the bridge pickup routed to the twin and the neck pickup routed to either a Yamaha B100/115 combo or an Ampeg SVT and 810. I also ran biamped with the Twin and SVT. I used an Orban 672A for processing, so the crossover could only be run down to 200hz. I even used the Twin full-range in a cover band. I elevated the Twin and ran a mic to the PA.
Keep in mind the JBL were pretty robust speakers. Most open back guitar speakers will fart out and suffer damage at a fairly low power level.