You will def have to put in some work on the nut to get the string to sit properly in the slot that was cut for an E string. . We have some songs in drop A. I actually use surprising light gauges. Dr hi beam .125. I just play a little closer to the bridge when dropping to A to so the tension doesn't feel weird.Hey, so I have a 2000 american deluxe precision bass and am wanting to tune it to D standard and drop the low string to A. I was planning on buying .145 kalium/circle k string. Do you think that my bass could really deliver a good/clear tone with such a low tuning and heavy gauge? Also, I would also expect to have to file the nut and set the intonation for the heavy string. Thoughts?