well, first off, sorry to hear about the home situation, hopefully it won't have too much impact on you and your life. good luck with that.
As far as more portable amps, there are just a slew of high quality, low weight, high output amps out there right now. Think Genz Benz Shuttle 9.0, Shuttle Max 12 (2 600w amps!), Mesa M9, Markbass SD 1200 or Little Mark 800, GK, Carvin .. etc etc.. the list goes on and on.
As far as cabs go, Neo's will be your friend. If 4x10 is really a must, but portability is key, you might want to think about 2 (or 3) 2x10's instead. You get more modular and still have a "4x10" when needed. There is no end of relatively light weight neo loaded cabs on the market right now too from the same names l listed above for amps.
Another way to go is to look at some of the killer pro level combos available and add an extension cab for gigs. Example would be a Mesa Venture 2x10 combo with an added 2x10 extension cab. Keep the extension at your rehearsal space and just move the combo. You get a pro level 600w amp driving either 2x10s stand alone, or 2 2x10's with the extension. Easy to move, tons of power, great tone .. what's not to like? Other manufacturers have similar pro line combos too.
Ultimately, while we can make broad suggestions, you need to decide what gear fits your plating situation best. The good news is that with few limits on cost, you will have no problem finding something that will work for you.
good luck