(To be clear, this quotes La Bella as quoted by @Sideways S.)
As I have experimented with custom gauges, I have come around to what the La Bella people say here: we can balance tension from string to string easily enough looking at the numbers, but that won't necessarily balance tone (which I suppose we can at least partly quantify looking at frequency responses, though they'll vary between instruments and players) or feel (which we could probably quantify somehow, but I have a hard time imagining how, and seems even more subjective than tone).
I have put together custom sets through Stringjoy (who doesn't appear to do flats) and Curt Mangan (who does) (excellent customer service from both, by the way). I selected gauges based on the most easily quantified metric: tension. I might have noticed the more even tension, or I might have imagined it; but it didn't make a huge difference in feel. Using only my ears—subjective, but also the only "measurement" that ultimately matters—I thought "standard" gauges sounded more balanced from string to string than the gauges I chose, even though I knew my selections distributed tension more evenly. I might continue to tinker with custom gauges because I enjoy it and it doesn't cost a whole lot to try, but when it really counts, I think I will lean on the expertise of people who have made it their business to figure these things out.
@Sideways S, based on my limited experience and La Bella's extensive experience, I would suggest finding a set that suits you better if you've got one that doesn't feel quite right to you. And I bet the La Bella people would happily help you choose.