I'd be thinking more of a high pass in the return, not in the send, though either would probably work OK. I do understand that the contoured blend in the Dirtfixer isn't a simple low pass/crossover. I think it might work better if it was, actually - it doesn't give enough mids or highs to be clearly present in the resultant mix, but it is there - I hear it as being a bit in the way of things, but not enough to cause major problems.
Anyway, if you want to experiment with what I've run into, try running a Tumnus (little one) versus an MXR Sugar drive. both are Klones, but the Tumnus has a different low end (more extended) than most. With The Tumnus, you try the polarity swtich (aka phase) - flipped vs non flipped, and there isn't a clear winner. One sounds a bit better, but it's subtle. With the Sugar drive, one polarity sucks out quite clearly, and the other is solid - there is a position that works. It's all a crapshoot - whatever phase and amplitude response there is between circuits may work together, it may not - it's two filtered half systems married together in a bit of a shotgun wedding. If you have a sweepable crossover point (or two), you have a knob where you can line up the phase response better (likely not perfectly, but better).
The EQ is on the return of the loop so if you turn down the bass control on Dirtfixer you are effectively high-passing the output of the pedal in the loop.