I went a little bananas and picked up both a Line 6 Pod Go and a Zoom B6. I got the Pod Go (PG) maybe two month ago and the B6 has been here for not even two weeks. A few thoughts and observations, plus a little about where I'm coming from...
I'm a bass guy with a gigging rock/dance band and I also noodle at home with a guitar here and there. Gotta have my harmonic option and some power chords when Uncle Dee is on the radio doing House of Hair!!

I haven't done much for bass effects - mostly try to drive the bus - but our funky material could stand to be dressed up with some envelope filter and synth sounds. I'm sure I'll think of some other stuff as we keep on in that direction.
I got into a chat with a GC guy who has been pretty honest and helpful in recent history with advising me on this and that. He had super high confidence with the PG for doing both guitar and bass stuff - he also plays both instruments and gigs - and that seemed like the smart route for me. One unit that could maybe do everything I want for now. I looked at some demos online, traded in some old stuff, and gave a Pod Go a new home.
I found several REALLY nice guitar sounds among the presets in the PG, but it doesn't come with a big bundle of bass sounds right out of the box. So then it was time to start digging into putting my own patches together. Although this unit isn't insanely complex, my personal learning curve has been a little steep. The itch was still there to grab a B6, so I pulled a what-the-heck and got one.
As soon as I switched this thing on and started hopscotching through the presets, I was feeling much more at home. It's obviously aimed directly at the bass world. The touch screen is remarkably easy to use, but there are also corresponding knobs under the screen that make it easy to tweak amp and effect settings, overall gain and volume levels, etc. The touch screen pretty much tells me what I can do, where I can go from here, but isn't so busy that I've gotten lost. Generally easy enough to either keep it simple or do a good bit of tweaking.
Tuner - big (easy to read) and plenty accurate for me. I need to either detune or keep a second bass handy for a couple of our songs that don't have standard tuning (I play 4-strings), so having the dual instrument inputs will be a very big help there. Calling up a drum track for some play-along using the touch screen... EZ! And both units have a USB connection, although I won't be needing that at all for the time being.
I haven't started building my own patches in either unit yet, but the B6 has a lot that are ready to either use or tweak into shape as is. I have a gig this weekend and I don't want to embarrass myself by trying to do too much with this board before I really learn my way around it, but I know that it can help me with a couple of things right now. I'll just need to be careful to have the volume settings on a couple of patches leveled so that I don't get stupid loud or too quiet when I call up one or another.
I can jump in and swim with the B6 right now and I also still have a good chunk of ground to cover as far as learning how to setup my own sounds and arrange my patches to work with our set lists. The good news there is that its "Memory Mode" gives us exactly that - four patches in a row in one bank so that different sounds can be lined up at the ready as needed. This bank for a certain funk medley and perhaps another bank with a slap patch, a synth, and an auto wah all right next to each other on hot standby.
The Pod Go is packed with a LOT of stuff and I think that if you can sit with one at a shop - I've seen one set up on a demo stand at a local GC - to see what it's about, that could be illuminating. The GC staff might be hot to sell those units over the B6, since the PG's are in stock there, but at least somebody might be able to show you a few things on a PG and get you going with a decent introduction. My PG is waaaaay beyond the kidney shaped desktop POD (for guitar) I had a few years ago and while I'm sure that it's going to impress me going forward, it's also going to take me a while to get to know it.