I'm a pick player and recently I've been having a lot of pain fairly quickly, which isn't normal. The only thing different I've been doing is using different gauge picks and practicing different things, such as string skipping and more funk driven lines. Sometimes the pain travels from my thumb to my wrist, and lasts for awhile after I'm done. Have you guys ever had this happen out of the blue? I would understand if I was new to using a pick, but I'm not.