In the early days of Talking Heads, when they were a trio and David Bryne's playing was much more strummy, Tina's bass lines were often the only other melodic element (besides the vocals). As the band got more rhythmic, her use of space and discipline about using hypnotic riffs were a major, major part of the band's sound. David Bryne became a really cool guitar player, too. It's like Joe said above: it's funky, but in a lower East side art scene way.
Plus, Tom Tom Club "Genius Of Love" is still THE jam.
Plus, Tom Tom Club "Genius Of Love" is still THE jam.