Some of the higher end tube pedals include DHA, Swell, Freq Central. They probably won't exactly replicate the Mesa sound but maybe they can enhance it. I hear you, though. I'm currently on the fence about whether to upgrade to a Glockenklang rig or keep the Mesa Boogie Strategy 400 Power Amp I have and get some high end cabs and a preamp to pair with it. If the Mesa could do what it does into one cab and a low volumes for those small venued gigs it would be a no brainer....but I need something that's versatile.
