For me, it is a 2-step process every couple months.
I used to use a headset at work where the earpiece actually went into the ear - like a rubber earplug. All of the sudden (actually having built up for months) I would not be able to hear out of that ear.
I used a commercial cleaner, and it smelled like HP. Hmmm...maybe HP would work fine as well.
That would soften it up, and some wax would come out.
Then I would go over to the sink and fill it with lukewarm water, and use a small rubber bulb to suck in warm water, insert it into my ear, and then sqeeze (like the dickens). This resulted every time in large black chunks coming out of my ear. It also always sounded like I got a new ear (exaggerating) like.....wow, I can hear the birds again.
In any case, I think the bulb was one I got for my son when he was a baby - it was used to help suck mucuous and stuff from his nose. Look for it in the baby section at your local pharmacy.
Good luck!
The attached pic was from bio-buzz.com. I don't know who they are, but since I snagged this pic, I figured to give them credit.