... as mentioned, guage becomes preference as much sound choice and feel... I have the ECB81 45-100's (Med lights) on most of my J's, but on my VM Jazz I have the 40-95's (Super Lights)... I really like the little nuances of the lighter gauge Chromes for the most part, and Duncan Designed pups really seem to work well with them for me ... it really becomes a try as you go sort of thing for preferences ... I have not used the 50-105's (Mediums), and dont really see the need to go there, and I have a set of the Custom Light Chromes (40-100) waiting in the wings if I ever get one of projects done ...
Edit to add: I just saw a thread on here where some folks are wanting a heavier gauge than currently available for Chromes ... I am really starting to appreciate the lighter gauge Chromes and will be trying to ween myself that way a bit more .. JMHO