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would this reduce normal single-coil hum?

If all it is is a couple of isolating transformers, then no, it won't get rid of single-coil hum.

No idea how the new EH Hum Debugger works, but it would seem to me that separating out hum from a signal, and eliminating one while leaving the other completely unmolested is a bit of a case of "too good to be true." Still, worth a try.