Here's my take on the 410 NEO. I hope this helps the OP.
I purchased my 8 ohm 410 NEO three years ago and it's been a good addition to my rig with its low weight (yes!) and very nice, clear sound. I had one speaker go out with voice coil rubbing just after the warranty expired (GK absolutely kills you on 10" 32 ohm speaker prices!) but since then I've had no problems with the speakers. I've read reviews, however in which several folks have complained about the durability of the speakers but as I said, aside from the first one I've had no further trouble in that department.
I play an Ampeg PF800 through it and the cab has handled that without issue as long as I don't get stupid with it. I mostly play clubs and bars without PA support and it does well in that role. It can really hit the low notes and it does agressive very well and it fills the hell out of a room. You won't have any trouble being heard with this guy. The cab supports bi-amping if you have a GK head and the special SpeakOn cable, but since I have an Ampeg head I keep it in full range mode and after monkeying with every position on the tweeter volume knob, I now keep it at 12 o'clock.
I will say that as I've developed an ear for what I like, I've struggled to find something that satisfies me with this cab. I play in a band that does 50's through 90's music and I've come to prefer an old-school, vintage thump and I've been inconsistent in getting a tone that works well for me in every situation. I can certainly accept that it's mostly my fault, but the cab isn't making it as easy as it might be for me to learn how to get there either. To my ear it seems to have been engineered for a specific range of sounds rather than to be a jack of all trades, but it's possible that says a lot more about me and my ear than it does about GK.
It's a reasonably well-constructed cab of around 48 pounds so aside from the bulk of the box, it's easily transported. It's not what I would call extremely durable. It has been gigged moderately in a moderate volume classic rock cover band, perhaps two to three times a month but even at that moderate pace it's showing some wear and tear. The handle plates on the sides are not the strongest metal and after repeated use have bent a little. The casters (a fantastic feature) don't roll as smoothly as they did when it was new but they haven't broken either.
These issues don't affect the sound at all but I expected a bit more robust construction for the upper mid-range pricing on these cabinets. All that said, I don't doubt that the GK offering is on par with other manufacturer's cabs in this price range, but at pretty close to $800 retail, who can blame me for expecting a little more?
If I were looking to buy again today I'd probably take a much harder look at Ampeg's line of cabs to get the vintage vibe I'm seeking. I had a Rumble 410 (V2) cabinet before this one and the GK cab is much superior to it, but I haven't compared it to the new line yet. I'll probably be replacing it sometime this year, and I hope my current cab finds a good home that appreciates what it offers much more than I do.
and it would be cool to have a very different cab from the 410.
