Usually not found in amps, but available in some external DI boxes, is the ability to tap a signal off the speaker line. Especially useful, though, is one of these that has compensating circuitry, that rolls off some of the high end to more closely approximate the response of speakers (speaker cabinet simulation). Otherwise you'd end up with really clanky highs (amps have a lot of HF hiss for various reasons). But for the dudes who play SVTs and the like, other than micing, this would be handy. You'd hear any amp characteristics being generated (but obviously without cab influence). Other than just liking a particular model of microphone and how it sounds with your rig, this is pretty practical.
Myself, I'm a pre-EQer.
Myself, I'm a pre-EQer.