Even though bass players are expected to play like machines, we aren't one.
Years of experience tells me that if you play a lot, you need to find a gauge and tension that doesn't cause pain or injury to your hands. If you've ever woken up the next day from playing and your hands hurt, are sore or swollen, you are doing it entirely wrong. You can do permanent damage to your hands and fingers, create carpal tunnel syndrome in your wrist, get tendonitis or bursitis in your arms and hands and, set yourself up for arthritis later in life.
I went through some of this stuff in my late 20's and figured out (with the help of an orthopedic doctor who happened to be a bass player too) how to deal with it. I had to change the way I played entirely or physical problems would have eventually ended it for me.
For a number of years I've use very light gauge strings (35-50-70-90-125) and Labella 760XL (39-56-77-96) flats. I play with a light touch and let the amp do the work, I can dig in and get all of the power that I need with no problem whatsoever. Also, I find that the lighter gauges and tension make the bass sustain longer, my playing more nuanced, and I have more control over the instrument.
I am a big fan of balanced tension strings for a number of reasons too - they feel great and stabilize your technique as you aren't physically compensating for different tensions all of the time while playing.
They are better for the neck of the bass itself as the tension is even across the entire neck and the relief (bow) is the same on the bass and treble side of the neck making the action consistent and the bass play more accurately in tune.
The other big issue for any bass is having the correct height at the nut. For one thing, if it's too high it will make you have to work harder and will fatigue your left hand.
More importantly, the nut sets the stage for how the bass plays in tune up the entire neck and on how the overall action feels too.
Here's how check it... Press down the first fret. Generally, the nut height should be about the same distance open as the string is from the 2nd fret (while holding down the first fret). Another way to check is take a chromatic tuner, play the open sting, get it perfectly in tune, on the tuner and then play the first fret... check the intonation of that note. If it is sharp the nut is too high and needs to be lowered. A bass will intonate perfectly at the 12th fret but if the nut height is wrong, the bass will still play out of tune. Don't try and lower the nut yourself! Find a good technician, with the proper tools, that you can talk to and be present when he works on your bass. Together you can get the bass set on how you want it to feel and play. Such a small adjustment can do wonders.