Sorry--I should clarify. Monique Line Out -> Channel 1 in on a QSC PLX1802 power amp -> one 8-ohm bass cab per channel at 330W each (I have bridged to 1800W on occasion, but 660W has been more than sufficient--I'm not touring in a reggae band, for goodness' sake).
I do have a couple of JBL PRX powered PA speakers that I've run through for fun, and they're great for full-range "sound of your bass," but they're usually dedicated to other purposes. If I really was going to go that way, yes, I'd consider whether I wanted a cab sim and filters between the Monique and powered speaker. A good number of people strive for that full-range thing with their Green-he's-got-to-have-grown-up-by-now systems.