The DNA 210 is a beast. Solid low end, good low mid presence, good midrange presence, Great upper mid detail and good high end. Compared to the 410XLT, big differences.
The 410XLT:
Loud and projected bass tone farther than most 410's.
A very growly and edgy midrange 300hz through 800hz which accounted for a very cutting bass tone.
Solid low end, but never super low.
Good upper mid growl, but the tweeter did not have much high end coming out.
In summary, the 410XLT was a very "colored" cabinet and you got a unique tone out of it. The DNA 210 (that I own) is much closer to representing the rig you are running through it. it's cleaner overall and does not have the growly midrange content. It has a much better low end response though, and is clearer in the highs.
I used to use the 410XLT with an Ampeg SVT 4 PRO and a few other heads. With an Eden head, the 410XLT sounds much better - more low end, punchier in the mids, and sweeter sounding highs.
The DNA 210 is loud - it will cut through the mix. You really can't go wrong with it.