No issues that I know of, or experienced using the combo cab without the amp in it. You do have to get yourself a Female/Female 1/4" adaptor for the cab.
I would go with cabs with the same ohm rating, and not mix them ... it's just simpler IMO/IME.
At various times I used a 12+15 and a 12+12 config. I liked the 12+15 rig better as I felt like the 15 handled the power better and as long as you manage the low end EQing, the 15 also gets just a bit deeper/fuller .. again IMO/IME.
good luck
and Merry Christmas !
I would go with cabs with the same ohm rating, and not mix them ... it's just simpler IMO/IME.
At various times I used a 12+15 and a 12+12 config. I liked the 12+15 rig better as I felt like the 15 handled the power better and as long as you manage the low end EQing, the 15 also gets just a bit deeper/fuller .. again IMO/IME.
good luck
and Merry Christmas !

<sigh.>
