Advice above about HPF, EQ can help you be heard better, but if you don't have enought speaker surface area, you're not going to keep up. My biggest question is what kind/size and how many drivers are in the cab? Driver efficiency is important as well. A 115 wouldn't have a chance, you'll need a lot of speaker surface area to keep up with all that, unless you go through FOH. You may need two 212s, two 215s or an 8X10.
While it's possible preserve and protect your hearing, modern medicine is VERY limited in RESTORING hearing, so once it's gone, it's gone. And the accompanying tinnitus can be maddening, so yeah, protect those ears!