You can go with a sealed cab by simply blocking off the port. The 12LFA will yield a non-peaked bass response, with moderate bass depth (F3 around 76 Hz, F5 around 63 Hz), AND sufficient power handling (approx. 180w at 40 Hz and lower) if excessive bass boost is not used. Results with the S2012 are similar (F3 around 72 Hz, excursion limited power handling around 200w below 40 Hz), but with about 3 db more sensitivity, more prominent upper mids, and several pounds less weight. Using the stock port, both yield about 10 Hz lower F3, over 300w excursion limited power handling to around 30 hz, but with only around 200w power handling in the mid-bass. I suggest that you try the cab both ways (sealed and ported), and choose the one you like best.
As long as you are tied to the stock cab configuration, these drivers are your best option. Either way, you will have more power handling and more mids. However, you will have cabs with a lean bass - very articulate, but lacking the prominent mid and upper bass of the stock cab. To get good Pbass tone you will need to boost the bass (probably 3-4 db), and this will reduce maximum loudness somewhat. So, sealed or ported, you will gain a fair amount of power handling, and more upper mids. If you only occasionally ran into power handling problems (like fart-out), these gains may be just what you need. If you were short on power handling fairly frequently, these gains are not likely to be enough.
For best possible performance, blocking the stock vent and adding tube ports is the best way to go. If you do not want to add tube ports (or cut back the vent shelf and deal with chuffing), it may be best to sell the stock cab and buy or build a cab that will deliver the tone and power handling you are looking for.