... I want to spend $300-500 shipped, and ideally under 50 pounds. 2x10 4x8 2x12 are possible. I'm more interested in 8s and 10s, but I would consider 12s. ...
Ampeg 210AV is rated at 200 watts at 8 ohms, and I don't want to risk frying it with the 375 watts my amp pumps out (but the size is attractive)...
... I wouldn't recommend only one 210AV under almost any circustances ... even when one would work, I usually always just use the two (other than rehearsal and coffee house type deal) ... the difference between one and 2 is substantial, and at 26 lbs each and a one sq foot box to carry (with handle on top) is more than attractive for weight and stage space ... I use a pair with 500 watt head and have no worries ... and at $200 each shipped used, and $250 new (with 15% off) you are in your price range, and both other criteria bolded ... should they not be your cup of tea, they will sell fast on the used market
JMHO as usual...