But fewer blisters with alternate picking? Or maybe not - my last big bout of playing last week resulted in one massive blister on my middle finger only - the index finger was totally fine.Another night of playing, some Who, some Oasis, hands feel OK. Got a blister on my fingertip. Dropping the pretense of alternate picking with the index and middle finger. Just going index with occasional assists from the middle finger. Damn the Establishment of alternate picking.