Exactly what I'm thinking about, in the summer (Mem. to Labor day) I do 2 gigs a week minimum that requires me to park and walk a 1/4 mile to a ferry, load my stuff on the boat (and leave it unattended) then after it is unloaded by a crew from the boat I have to walk on a wooden board walk to a club. It's usually really humid and most time 100 degrees inside and the power isn't always reliable. No PA support on these gigs as well. They are actually very fun as allot of young ladies make their way in with beach attire on
Only issue seems to be so far is protecting the knobs on the top of the combo....And of course price, I haven't heard anything yet.
That's why I moved to the Puma500/s212 from my previous 410 rigs (even though I still own those cabs). I get 80% of the wump, in a much smaller package. And, with that little 212 and the Puma in a bag on top strapped to my Kart-a-bag 600, I can walk blocks and block, up and down stairs, curbs, etc. without even thinking about it.
That combo looks awesome (and the TecAmp covers are the most padded I've experienced), but I need my tweeter, so that combo wasn't an option for me. It looks pretty awesome though! I"m not a big fan of those little tilt back wheel things, but in some situations, they can work great.
Also, as we discussed in detail earlier in the thread, the combo is 8ohms internally to allow for adding an extension cab. Since I never use two cabs on a gig, the ability to put the full 500 watts of the Puma500 into the s212 was a positive for me (again, not so much for volume but clean headroom). Not a huge issue there, but for my playing style (occasionally slapping and liking a bright tone), the extra wattage and tweeter in the stand-alone version fit my needs a bit better.

