It's a bit frustrating to be making these choices based on hearsay, but I really can't really tell the difference between 10s, 12s, and 15s when I'm just jamming in a music store. Sure everyone loves a 410, but so much of that is historical rather than based on actual listening.
there isn't really going to be any difference between speaker sizes - a speaker's size makes no difference. The cab that it's in makes the difference. instead of comparing 12s and 10s and 15s, compare individual cabs that you like the look of - cause that's all speaker size really changes, is the look