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wierd sound

Hey everyone,
I need help fixing something:
my cabinet is making a funny farting sound. I have the following equipment
I have an Orange ad200b connected to an ampeg 410HLF. I use Musicman bass.
On the orange amp gain cranked up a about halfway & the volume cranked up halfway. When i am playing hard & i hit the B note on the E string, i get a weird fart sound. My speakers appear to be not cracked or anything like that. It is only that note on that string. If anyone has an fix to this, please let me know.
Thanks in advance,