Not really...IMHO, sound needs to optimized for each location and use. In other words it should be tailored for onstage monitoring and also for FOH for the house mix.
If the bass player uses a 210, 810, or IEM it is part of the equitation that must be considered for onstage monitoring. Ideally it should have nothing to do with how the signal will be processed or mixed at FOH. However, any time you are sending a Post DI signal to FOH, the way you adjust your sound on stage impacts the signal you send to FOH for the main mix. Also unfortunately, the reality is the louder and more bass-heavy your the mix is on stage, the more likely it will have an impact on the FOH mix. Essentially a loud, bass-heavy stage mix takes control away from the FOH mix.
This problem with acoustic crossfeed goes both ways. In other words, the PA mix also degrades the stage mix. Often it is difficult, if not impossible to strike a compromise where everyone gets everything they want. As a result, pro musicians generally learn to work with some degree of compromise. They get what they need rather than what they want.
In the event that you are using a modeler, IMHO it really does make sense to use some sort of FRFR cab if you are not using IEMs. The idea is to design a patch that sounds authentic to an SVT and 810E through a FRFR system like a PA. If you create a patch that sounds authentic through an actual 810E, the signal you send to FOH will need massive EQ and processing before the sound coming from the PA is similar to the sound you hear on stage. Of course if the Helix has two outputs, and you can leave the output driving your cab flat and apply an authentic 810E IP SIM to the output that is sent to FOH, maybe you have a chance.
I know for a fact that modelers can sound as good, if not better than real amps for live work. But it really does take someone who has an ability and feel for adjusting all of the parameters. You really have to dig in and develop an understanding for how sound, amps, and PA gear works on a certain level. You also need to use a bit of common sense, because there are a lot of ways to screw it up.