I've never heard this about AI heads. I've made some similar comments about EA heads. Basically, here's what I said in essence about the EA iamp I had:
On most amps, the best strategy seems to be to treat the power amp (master) section as being totally clean with little or no tonal variation between fully off and fully on. The preamp, OTOH, tends to color the sound more the more you turn it up, so normally I set the power amp at noon, then turn the preamp on as little as possible (usually 9 o'clock or so) to get the cleanest possible sound. Then, if i need more volume, i turn the power amp up. This is how I still use the AI amps.
With the EA iAmp, there was a "sweet spot" on the pre which was usually in the 12-3 o'clock range which had to be found to get the optimal sound, then the power amp could be used for volume. The basic feel was that of an "input level", and the LED display on that amp showed when the input signal was strong enough to use.
Hope this wasn't too confusing.