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My compressor is absolutely always on. I find that not only does mine compress, but it beefs up and brings out the bass in a way that makes it super punchy! ( I use a Taurus TUX Wojtek Pilichowski ) But besides my comp, if im not playing with an amp, or playing with one that is not exactly to my taste I will keep my preamp pedal on and connect through the FX loop ( Markbass MarkVintagePre )