I too have had just about every single and combo of speaker/cab sizes. 1x18, 4x10, 2x10, 1x15 etc etc. But I recently purchased a RevSound 212T and I have to say I'm in heaven. I also have two of the PJB C4 5" cabs for home practice and very small gigs. The 212T is aligned vertically so it takes up very little floor space which is a HUGE help for the kinds of gigs I play. Plus, it removed any stress about which cab to bring. I was always thinking and re-thinking my decision to bring just the 15, just the 210, both and so on. This eliminates that decision and allows me to stress on just which bass to bring and whether to bring a backup, change the battery...you get it.
Finally, the single cab is light at only about 32 pounds. I can basically do a one trip load-in/out and that is great. And because it's on the tallish side, I can hear it without propping it up on something or tilting it back, even if I'm pretty much right in front of it.
Love what you play and play what you love!