You can still find used Shuttle's in many flavors out there. They have speakon & pre/post DI that you mentioned. A used Shuttle and an MXR pre-amp is the combination that I'd recommend.
Appreciate that... I'm just wary of used Class D amps (or any amps/cabs). Arguably, it's harder to see what they've been put through than with used basses. Anyway, after hearing impressive demos and reviews, I'm leaning a bit closer to the Genzler 800, I'm assuming (perhaps incorrectly) that it carries on the Shuttle's tonal tradition.