AL!EN BASS, for your application you NEED a system with a mid driver. 4x10, 8x10, 2x12 are all going to give you problems.
If I understand correctly, you are using low tunings (F#) AND slap/pop play. This puts an immense amount of strain on your drivers. Think of it this way--you are putting a very low frequency signal and high frequencies (from slap) at virtually the same time. No woofer can handle this at high power and/or long periods of time. This is where crossovers really help. You can send lows to the woofer, mids to the midrange, and highs to the tweeter. A TRUE 3-way system like a fEARful will really help your cause.
Now, back to what dhomer was saying. A high pass filter could also help save your drivers and give you a little bit more efficiency. I don't think the Carvin has any DSP crossovers built in, but you may think of one in the future. At a minimum, HP at 23 Hz, but to really be out of the unloading zone, ~35 Hz would be better. This cuts into the fundamental frequencies that you are putting into the cab, but most of what you hear are harmonics anyway.
Unfortunately, much of this comes from the tradeoffs you make with a ported design. Yes, ported can go lower than sealed, but it is easier to blow a driver with a ported cab. Use drivers with high xmax, proper crossovers, and if available, limiters and you should be ok.
Another note: You say you are using a compressor. Compressors can also be dangerous. If you heavily compress and make up for it by cranking the power, this is another classic way to blow your cones.