I have several things to say about this....
"the complexity and drama of tubes: preamp tubes are generally not problemtic, at all. I think in my entire career, I've had one fail. I've been gigging for...35-ish years now, and had more solid state stuff fail on me, fwiw.
"go with the smaller cheaper..." it is in fact true that the MB800 is a little less deep than either the MBF500 or MBF800; but, I personally prefer the tone of the MBF. So, I'm glad it's there as a choice. The cost diff b/t any of those isn't all that significant, if you start looking at some other manufacturers "top of the line" offerings; IMO.
ymmv, etc.
+1 I would agree with 'generally not problematic' for sure (although an awful lot of posts on TB with various tube pre's regarding 'I'm hearing a crackle... what is it!), but if I can get rid of one more level of complexity and not really lose anything, that is a bit of a no brainer for me, especially with IMO the VERY minimal impact of the tube section of the MBF500 that I noticed (and that minimal difference seems to carry over into the MBF800 from the early reports).
I guess the big difference would be when you use the 'overdrive channel', since I did hear quite a difference in the nature of breakup from the 'F' models versus the more classic grind of the GK SS preamp. I greatly preferred the MB500 in that case. However, I can TOTALLY see many who like that sort of tone preferring the 'F' models, and I assume that is their primary 'reason for being'.
Just IMO and a bit of IME.