Thanks everybody, great responses.
What prompted the question was that I recently picked up a 175-watt*, 1x10 combo as a compact grab & go alternative to my 800-watt, 2x10 rig, and I’m realizing that I have no clear idea as to how to draw the line between a gig where I need the latter and one where the former is enough.
*The head is 350 watts into 4 ohms, so with just the 8-ohm combo cab, it’s a 175-watt rig.
I have a D350 and typically use it on two Mesa 210 cabs. I can and have used with a single 210 or a single 212 so running it at 175w, and it still had plenty of volume even outdoors for hearing myself onstage.
Gig pictured below was an outdoor university party, the D350 on a Powerhouse 212 @ 8ohms.