Idk where it would be best suited in the chain honestly. I've got mine before my main board. On its board, the sister board, I plug my bass into the whammy > rails > JTDT (fuzz)> meatbox > ms60b > the main board. Which has the tuner first.
So again, not sure. I tried the meatbox before everything on my sister board yesterday, but I didn't dig it that way too much. So I put it back to where it was, the way it is now. It's still pretty early in my chain. I like it where it is right now. So I've got fuzz before and after it. The whammy and fuzz into the meatbox are pretty flippin awesome! I still haven't come to a solid spot for the octave on the meatbox. It's tough figuring if I want more clean bass or effected, fat, synthy bass. Guess it depends.