My first amp was a Peavey Mark 3 into a Mesa/Boogie RoadReady 2x15. Played that rig throughout high school and college...
The 2x15 from Mesa will sound great with the EV speakers. It has very convenient handles located on the sides, the casters are immensely strong and the roadcase that the cabinet is built into will take some serious punishment before even showing any scarring.
As everyone has already replied, the main liability with this cab is the weight. The cab actually weighed more than I did when I got it at 14 years old (I've since "caught up") and loading it into a van or truck wasn't so much difficult as just physically taxing. The RoadReady cabs only have 1/4" inputs so using a Speakon-out amp will require special cables (buy at least two). And the rugged appearance can deceive some bassists into thinking that 2x15s can crank louder than they should when they're expecting the responsiveness from 10"s (that's how one idiot that I loaned the cab to blew both speakers...never loaned out gear again).
As much as I loved that cab and had great memories of it, I traded mine in towards an SWR Megoliath and don't regret it.