EDIT: Just been noodling on the One 10/V4b combo again. I cannot believe just how good this combination sounds. The V4B seems to really open up the One 10. Absolute tonal heaven..... common sense does say that since I bought the One 10 to be part of a mini rig it seems a little silly.
I run an Ampeg PF50T into my One10 frequently, I'd imagine it sounds much like your V4B and One10... it is sweet. There is ONE room in town where the frequencies match up in some perfect storm to where I can't use the PF50T in it, though, with One10 or SM. PF50T+One10 is what's set up right now in my den as my practice/home setup.