Interesting. My ongoing experience is quite different. I say ongoing, as I bought my M3050 set (045-105, for my Midtown) a couple of weeks ago. What is similar is that they are definitely taking some time to break in.
For me, though, the D and G strings sounded great from the start, and the E and A strings had quite a bit of growl and grind. This surprised me, as I was expecting the opposite. Some posters here on TB reassured me that they had similar results and I should just be patient.
Now, two weeks later, the E and A are settling in very nicely, and the strings' tones are balancing very well. Last night I was able (for the first time) to get the muddy tone in the low register, with the neck pickup, that I was hoping for.
At this point, I certainly love the trend...
Also, the strings out of the package were quite silky feeling.
Maybe the different sets are made differently? Maybe it depends on who is doing the winding?
Regardless, patience is certainly the key.