I don't know why, but I can't stop myself from countering some of this rubbish. You continue to mix the issues of box material, design of drivers, and cabs versus heads. Again, not trying to dog you as much as give you some things to think about, and a bit more knowledge about this stuff.
1) There is NO difference between reliability, durability, etc. between neo and ceramic drivers. The magnet material (which is allowed to be smaller and lighter using neodymium versus heavier traditional magnets) is the primary difference in weight (typically about 5 pounds per driver in weight reduction). For example, putting it in your terms of digging the Mesa gear, I would think there is absolutely no difference in reliability/durability between the Mesa neo cabs (anything with a 12 in it, at least for the last decade or so... they might have bailed on neo due to pricing at this point also), and their ceramic cabs (anything with a 110 in it). I've been on the road with neo loaded cabs since the early 90's, as have many of my freelancing peers. Zero issues or indication of differential relaibility/durability based on driver type.
2) BOX material is a different issue. Neo boxes made by Epifani, Genz, Bergantino, etc., etc. use high quality plywood and are braced and put together in the same way as ceramic driver loaded cabs. Since the neo drivers are not as heavy, you can use either lighter plywood (poplar), or in some cases, slighty thinner plywood to further lower the weight of the cab. I have neither experienced nor heard about a differential rate of 'issues' with well made cabs using poplar or thinner ply versus the cheaper/heavier (versus poplar) traditional plywood. Zero issue again.
3) There are some VERY high end boutique cabs that are really pushing the envelope of making a cab as lightweight as possible. Here, you have a point. For example, the current 'state-of-the-art' in getting the maximum wump in the smallest lightest box is (IMO and IME) the Arnopol version of the Thunderchild Compact TC115, made out of composite/fiberglass material. Of course, the Eminence neo 3015LF based driver in that cab is a pro PA speaker... totally top end, and will take more power, bass, etc. than virtually ANY other driver on the market, neo or otherwise. However, I would not choose this super-lightweight composite material if I was throwing this cab in a van every night with a lot of other equipment. Of course, in that situation, an uber lightweight cab would have little benefit anyway. However, that is a rare extreme example of pushing the lightweight/size thing to its limits. Of course, that cab will less likely have driver issues than virtually any other cab on the market, given the simply amazing, state-of-the art, almost subwoofer spec driver in there. To your point (kind of), there ARE crap cabs regarding box construction out there in any design.... no argument there. However, surely not limited to 'lighweight' boxes.
3) Your 'car' example which makes no sense regarding cabs, since again, there is NO trade-off between magnet material and durability or performance. The analogy has been used with the lightweight amps, primarily made lightweight due not to the power amp design (some are actually the traditional class A/B amps used since the beginning of time), but rather the power supply design. Lightweight amps use a 'switch mode power supply' (SMPS) instead of a heavy transformer. There again seems to be NO issue in reliability versus traditional power supplies. These type of power supplies have been used in top end touring PA's (especially for deep bass subwoofer executions) for years and years. Nothing new about it.
There ARE many who believe that a 'big iron' power supply will deliver deep bass better than an SMPS amp. Given the long-time use of SMPS amps in the PA industry, this seems a bit dubious. However, I have experience deeper low end 'presence' with amps like the DB750. the Mesa M6/M9, and the Glock Heartrock versus most of the micro amps I've used for years (gigged a Heartrock for a while). I have no idea if this is a hi pass/voicing issue, or just the ability of a big transformer to perform well in the deep bass area (for example, traditional designed amps like the AG500, the Thunderfunk, the Eden WT heads in NO way have better 'performance per watt' than SMPS designs at this point in time, which put the power supply argument on shaky ground). However, the point is, this is NOT a reliability issue/discussion at all. Per your car analogy, a class D/SMPS amp actually runs more efficiently and 'less hard' than more traditional designs when pushed.... again, zero validity in your 'car analogy', unless you use too little power and cone area for your volume needs. That of course would impact rigs of any design.
So, again, throwing all this stuff into one bucket of 'lightweight' is not a very good way to think about it. Again, if you dig your big, heavy Mesa cabs, there is NOTHING wrong with that. Nice sounding, high quality stuff. Just remember, many of those big Mesa cabs are loaded with neo drivers