At his best, he was as intimidating as anyone who ever stood on a mound.
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What did you learn today?
- Thread starter PWRL
- Start date
Getting some insights into the hope that's coursing through our veins — discovering for instance, among other things, that the AstraZenica vaccine is the long way 'round, the scenic route, on the same messenger RNA driven journey towards immunity. Cottoning on to the coordinates, the new, out-of-the-blue, legend
… Traditional vaccines, including some COVID-19 jabs, deliver antigens directly to the body.
But other COVID-19 vaccines, such as the Pfizer, Moderna and AstraZeneca jabs, use different technology.
Instead of delivering the antigen itself, the vaccines contain a genetic blueprint (or set of instructions) that tell the body to make the SARS-CoV-2 spike protein using the body's own cells.
To do this, the Pfizer and Moderna jabs contain a single strand of genetic material — that's the mRNA or messenger RNA — which is encapsulated in a protective fatty coating.
The AstraZeneca vaccine, on the other hand, contains double-stranded DNA, which is carried into the body via a weakened version of a common cold virus, engineered so it doesn't replicate.
The genetic instructions in the AstraZeneca vaccine come in the form of DNA, which is much more stable than mRNA. (Pixabay)"The DNA gets taken up by your cells, that DNA then encodes the mRNA, and then it turns into a protein … which is what your body is going to respond to," says Stuart Tangye, an immunologist from the Garvan Institute of Medical Research.
"The mRNA vaccine just skips that first step."…
Why some people feel lousy after a COVID vaccine — and why others don't
I smell a rat. … You may be thinking, that can't be good. But, at least i can smell it
TIL that Dunkirk is in France, not Belgium.
TIL that without John Muir, Stephen Mather, and Theodore Roosevelt, America probably doesn't have national parks.
TIL that Northern European ancestry may leave you with a gene that causes hydromorphone to be entirely ineffective. It was actually a few days ago, but just put this together with my GP. With the opioid crisis in full swing, the looks you get from ER staff when you have zero reaction to a full dose of that in your thigh is unsettling. The more you know!
Maybe you are a ghost, and that’s why you feel so funky.
Sleep study? I forget the threshold, but that is definitely in the "recommend CPAP" range, although I cannot say I was particularly fond of mine nor used it much. If you had a sleep study, then today I bet you learned how hard it is to clean that wax gunk that keeps the wires on your scalp. Hope all is well!
Yep, sleep study. CPAP in my immediate future. Moderate sleep apnea is 15 - 30. I always was something of an over-achiever.
TIL that my James Brown study book is actually at one of my brothers place which is a nuisance as we are in full Lockdown in Aotearoa
The upside is I did find 2 Comic series I didn't know I had purchased, The Crew and Power Man and Iron Fist vol2
The upside is I did find 2 Comic series I didn't know I had purchased, The Crew and Power Man and Iron Fist vol2
A bittersweet awareness: after a while, the Oxford jabber, whose effect lasts longer, will be on a par with the initially more efficacious mNRA jabber.
Getting a little — Oxford karma — boost there
Good for the spirits "
…The researchers at Oxford University … said, “Two doses of Pfizer-BioNTech have greater initial effectiveness against new COVID-19 infections, but this declines faster compared with two doses of Oxford-AstraZeneca.” …
Pfizer jab efficacy declines faster than AstraZeneca, both offer 'good protection': Study.
"
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TIL why I can't get paid decently for my work:
"Look: it’s not about the money for us. Never has been! It’s about passion. It’s about community. It’s about teamwork. It’s about making you think it’s not about the money for us, when it’s actually all about the money for us, and specifically not about the money for you."
We Will Do Anything To Get You Work For Us Except Pay You Enough.
"Look: it’s not about the money for us. Never has been! It’s about passion. It’s about community. It’s about teamwork. It’s about making you think it’s not about the money for us, when it’s actually all about the money for us, and specifically not about the money for you."
We Will Do Anything To Get You Work For Us Except Pay You Enough.
That’s good news! (For me anyway)A bittersweet awareness: after a while, the Oxford jabber, whose effect lasts longer, will be on a par with the initially more efficacious mNRA jabber.
Getting a little — Oxford karma — boost there
"
…The researchers at Oxford University … said, “Two doses of Pfizer-BioNTech have greater initial effectiveness against new COVID-19 infections, but this declines faster compared with two doses of Oxford-AstraZeneca.” …
Pfizer jab efficacy declines faster than AstraZeneca, both offer 'good protection': Study.
"
Don Everly Of The Everly Brothers Has Died At Age 84 - Don Everly, Half Of The Quintessential Harmonic Duo The Everly Brothers, Dies at 84
(And) in addition to her weird non-reaction to Serious pain meds,
We are of Irish stock…and that means that you can be sure there is some Norse blood coursing through our veins!
Enough ‘northern European’ lineage to have cursed our family with Alports Syndrome…
It’s a monster that has killed 5 of my first cousins, and my nephew, despite the fact that I gave him one of my kidneys.
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