Thompson upright -> Realist pickup -> HPF Pre-amp -> Carvin MB10
or
Carvin Icon fretless -> Carvin MB10
Korg Pitchjack plugged into the amp's tuner output.
That's it. At home, playing along with my CDs, I'll run my Fender into some pedals now and again, but no need for pedals in any actual playing situation these days.
EDIT: Oh, I just saw the post where I'm supposed to add insight ... I'm pretty much a classical and jazz musician these days, and mostly traditional jazz, so effects just aren't called for. I'm not anti-effect - I have a few I like to mess around with at home - but in real playing situations, even in rock bands when I was younger, I just never needed them much. Plus, I just love the sound of a pure bass signal - it's so rich and versatile, I rarely feel the need for more.