Power can't be transmitted over fiber and all of the peripherals you want to add just increase the number of places where a problem can occur.
Pickups are analog devices, period. You can digitize the signal once it has been captured by the pickups, but there's no guarantee that it will be any more reliable than an analog signal, passed through a couple of 1/4" jacks/plugs and a piece of cable. Fiber isn't able to be bent tightly, either. Kinds and bends that are tighter than the minimum bend radius degrade performance and in some cases, the signal will actually stop because the light will reflect back on itself. Then, there's the media converter needed at the amp. Do you want to manipulate the signal in the analog, or digital domain? You need to make that decision, too. Think Pro Tools plug-ins, for this part but you still need to deal with latency issues. Fortunately, digital signals have been pretty immune to marketing BS, unlike analog cables and plugs. However, I just saw that AudioQuest is selling high end USB cables, so I guess that ship has sailed, too.
I would bet that very few in this thread actually understand the requirements and signal properties of the cables and plugs/jacks we use. The standards were set over 100 years ago and, other than standing on the cable and yanking on it, we don't exceed the capabilities. If a guitar produces 12KHz, it's not even going to be audible, while coaxial cable can pass signals in the MHz range and even GHz, if the right conditions are met.
You must not like vintage amps- they won't be able to work with the digital signal you want.